Dear Esteemed HKLF Selection Committee,

I am honoured to apply for the Hong Kong Laureate Forum, a unique platform fostering collaboration between world-renowned scientists and young researchers. My passion for scientific discovery and commitment to advancing knowledge make this opportunity invaluable for my growth.

As a PhD student specialising in biomedical science and immunology, I focus on CAR-immune cell therapy with nanoparticle drug delivery systems. At HKUMed, I have worked on designing next-gen CAR immunotherapy applying NPs for neuro-related diseases, strengthening my problem-solving skills and enthusiasm for interdisciplinary collaboration.

The Forum offers a chance to engage with esteemed laureates and fellow researchers. I am particularly excited to discuss [specific topics of interest] and exchange ideas that shape future scientific advancements. The Forum’s mission aligns with my aspiration to contribute meaningfully to global science.

Beyond research, I am committed to scientific outreach and mentorship, inspiring future scientists. Attending the Forum will empower me to bridge the gap between research and societal impact.

I look forward to learning from distinguished laureates and collaborating with peers to address critical scientific challenges. Thank you for considering my application.

Sincerely,
Hank

At present, in order to address one of the most formidable forms of brain cancer, known as glioblastoma (GBM), I am engaged in research concerning the utilization of extracellular vesicles (EVs), with a particular emphasis on exosomes derived from effector immune cells, namely exosomes produced by CAR-Macrophages. This research pertains to drug delivery systems and regenerative medicine. Given that exosomes play a pivotal role within the organism and are vital for cell-cell communication, I am committed to elucidating the potential relationship of exosomes when exposed to various environments and conditions, while exploring their applicability as a therapeutic agent or as a carrier for neuro-regeneration. Simultaneously, inspired by the success of lipid nanoparticle (LNP) techniques employed in COVID-19 vaccines, another area of my research interest focuses on the application of a gold nanoparticle drug delivery system for the treatment of GBM, capitalizing on the high biocompatibility of gold nanoparticles and their ability to penetrate the blood-brain barrier (BBB), thereby facilitating targeted delivery of therapeutic agents to the site of GBM. Accordingly, my current objective is to devote my efforts to the application of both exosome and gold nanoparticle drug delivery systems, aiming to address GBM comprehensively, from treatment to regeneration.