I am eager to be considered for the prestigious Hong Kong Laureate Forum, a unique platform that offers the opportunity to engage with world-renowned scientists and young researchers from diverse fields. I am keen to participate in this select group and grow.
My ambition is to conduct impactful research with global implications. This forum is an unparalleled opportunity to broaden my perspectives on scientific advancements. I am particularly eager to learn from the experiences and motivations of these distinguished researchers, including Eva Nogales, whose pioneering work on the mechanisms of transcription and its dysregulation in disease has profound implications for therapeutic development. Their insights will deepen my knowledge and refine my mindset as I prepare for a research-focused career.
I am also excited about the possibility of presenting my research on bacteriophages as a platform for cancer vaccines at the forum. The valuable feedback I will receive from leading scientists and peers will help me refine my research ideas.
I hope to experience significant academic and personal growth by participating in this forum. The knowledge, inspiration, and connections I will gain from this forum will be pivotal for my future career in research and innovation.

The M13 filamentous phage has emerged as a promising platform for vaccine vector development due to its ability to be genetically and chemically engineered for targeted immunotherapy. In this study, we investigated the use of an engineered M13 phage displaying dendritic cell (DC)-targeting peptides on its p3 sites and SpyCatcher proteins on its p8 positions for the prevention of solid cancers. While intratumoral administration of the engineered phage has demonstrated efficacy in suppressing tumor growth and modulating the tumor microenvironment, subcutaneous injection has shown limited preventive effects. We hypothesize that this disparity is due to the rapid degradation of the phage in vivo following systemic administration. To address this, we are conducting dissemination pathway experiments to evaluate the biodistribution and stability of the phage under different injection models, including subcutaneous, intratumoral, and multiple injection regimens. These experiments aim to provide critical insights into the fate of the phage in vivo and inform strategies to enhance its stability and efficacy as a preventive cancer vaccine.