Entry Information
Mandadige Kalindu Shyamawarna Fernando
Dr
Male

21/12/1993
Sri Lanka
Passport
N8125
Sri Lankan
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+94743879582
30/7, Fonseka Road,
Kalutara
Sri Lanka
Mathematical Sciences
Life Science and Medicine
As a young researcher with a strong academic background and a passion for advancing knowledge in chemical engineering, I am eager to participate in the Hong Kong Laureate Forum 2025. My doctoral research at the Hong Kong University of Science and Technology focused on multiscale computational modeling of intrinsically disordered proteins, leading to several high-impact publications in renowned journals. My work has been recognized with awards, including the Hong Kong PhD Fellowship (HKPFS) and the Excellent Research Award for HKPFS awardees, underscoring my commitment to excellence in research.
Participating in the Hong Kong Laureate Forum 2025 would provide an unparalleled opportunity to engage with leading scientists and Nobel Laureates, fostering interdisciplinary collaborations and gaining insights into cutting-edge research trends. My experience as a graduate teaching assistant and lecturer has honed my ability to communicate complex ideas effectively, and I am keen to contribute to discussions on sustainable engineering and innovative scientific solutions to broaden my interpersonal and communication skills.
This forum aligns with my career aspirations to drive impactful research and inspire the next generation of scientists. I am confident that this experience will enrich my academic journey and enable me to contribute meaningfully to the global scientific community.
PhD Graduate
Chemical and Biological Engineering
University of Moratuwa
Sri Lanka
Department of Chemical and Process Engineering, University of Moratuwa
First Academic or Research Referee *
Prof. Ying Chau
Hong Kong University of Science and Technology
Professor
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Second Academic or Research Referee
Prof. Shantha Egodage
University of Moratuwa, Sri Lanka
Professor
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1.Best Graduate Teaching Assistant
Department of Chemical and Biological Engineering, Hong Kong University of Science and Technology
2.Excellent Research Award for HKPFS awardees
School of Engineering, Hong Kong University of Science and Technology
3.Hong Kong PhD Fellowship
Research Grant Council, Hong Kong
4.Best Research Presentation, Undergraduate Research Symposium
Department of Chemical and Process Engineering, University of Moratuwa, Sri Lanka
5.Mahapola Higher Education Scholarship
The Mahapola Higher Education Scholarship Trust Fund, Sri Lanka
Hong Kong University of Science and Technology
My research focuses on the development of multiscale computational models for predicting the behavior of intrinsically disordered proteins (IDPs) and their role in liquid-liquid phase separation (LLPS), a phenomenon critical to cellular organization and disease mechanisms. My work integrates molecular dynamics simulations, polymer physics, Monte Carlo simulations and computational chemistry to unravel the complex behavior of IDPs, particularly in the context of neurodegenerative diseases. I have developed an innovative computational pipeline to study the phase separation of IDPs, including IDP mutants, and their aggregation, providing insights into pathological processes like amyotrophic lateral sclerosis (ALS). The model has been further extended to investigate the charatrisitcs of IDP mimietics having potential applications in drug delivery and biochemical reactors which also undergo different levels of LLPS.
In addition to his theoretical contributions, I have explored applications of peptide-based systems for mRNA delivery, demonstrating the potential of designer peptides for efficient cytosol delivery of therapeutic molecules. My interdisciplinary approach bridges chemistry, biology, and materials science, offering novel solutions for biomolecular engineering and drug delivery. Recognized with an award for Excellent Research, my work exemplifies the integration of computational and experimental methods to address pressing challenges in biomolecular science and sustainable engineering.
Flash Presentation Session
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