I am thrilled to apply for the Hong Kong Laureate Forum, a unique opportunity to connect with contemporary and emerging scientific leaders. As a Ph.D. student in life science, I am passionate about advancing knowledge and fostering innovation in my discipline.

The HKLF's focus on enhancing young researchers’ understanding of diverse scientific fields aligns with my commitment to interdisciplinary collaboration. I believe that participation in the HKLF will empower me to engage in global scientific dialogues and promote cross-cultural exchanges. I am eager to share my experiences while learning from peers and mentors, aiming to translate these interactions into impactful research and community initiatives.

Thank you for considering my application. I look forward to the opportunity to contribute to and grow within this esteemed community.

My research interest focuses on the role of adult stem cells in aging and disease therapy, particularly in the context of skeletal muscle. As we age, the decline in tissue homeostasis and regenerative potential is closely linked to impaired stem cell function. Skeletal muscle exhibits remarkable regenerative capabilities, primarily due to its resident muscle stem cells (MuSCs). These adult MuSCs are maintained in a non-proliferative quiescent state, which is crucial for their resilience against external stressors and for preserving their stemness.

However, insufficient quiescence can lead to stem cell exhaustion, a phenomenon commonly observed in aging-related diseases such as sarcopenia. My current research investigates the regulation of MuSC quiescence and their resilience to external stress, including DNA damage and oxidative stress, which are prevalent challenges during aging. By understanding the mechanisms that govern MuSC behavior, I aim to identify potential therapeutic strategies to enhance muscle regeneration and mitigate age-related decline, ultimately contributing to improved healthspan and quality of life in aging populations.