Entry Information

PART 1: PERSONAL PARTICULARS

Name

Simone Leoni

Title

Mr

Gender

Male

Recent Photo

Recent Photo

Date of Birth

22/12/1996

Place of Birth

Switzerland

Type of Identity Document Held

Passport

HKID / Passport Number

X2621

Nationality

Swiss

PART 2: CONTACT INFORMATION

Email Address

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Contact Phone Number

+41786923939

Address

Schlossstrasse 117
Bern
Switzerland

PART 3: FORUM INTEREST

First Discipline to be Joined

Life Science and Medicine

Second Discipline to be Joined

Astronomy

Statement of Purpose to Join the Forum (max. 200 words)

I am eager to join the Hong Kong Laureate Forum to contribute to the exchange of ideas among scientists of diverse generations, cultures, and disciplines. As a young scientist, I am passionate about fostering collaboration and believe that networking with peers from different backgrounds is key to advancing research and innovation.
The forum’s emphasis on cooperation between different sectors to promote education in science and technology aligns with my goals of bridging the gap between academia, industry, and society. I am committed to contributing to initiatives that encourage cross-disciplinary collaboration and the growth of science and technology education in Hong Kong.
Joining this forum will provide an invaluable opportunity to learn, share ideas, and actively contribute to a global community of passionate scientists.

PART 4: ACADEMIC AND/OR RESEARCH INFORMATION

Academic Level / Position

Postgraduate (PhD)

Academic Subject / Research Field

Neurovirology

Current Affiliated University / Institution / Organisation

University of Bern

Location

Bern, Switzerland

Transcript 2

NEW-PhD.pdf

Transcript 3

HK-forum.pdf

First Academic or Research Referee *

First Referee Name

Stephen L. Leib

First Referee University

University of Bern

First Referee Position

Director of Institute for Infectious Diseases

First Referee Email Address

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Second Academic or Research Referee

Second Referee Name

Denis Grandgirard

Second Referee University

University of Bern

Second Referee Position

Research assistant

Second Referee Email Address

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Award(s) and/or Scientific Accomplishment(s) (if any) (max. 100 words)

• Travel grant ECCMID 2023
• Top rated poster ECCMID 2023
• Travel grant ESCMID Global 2024
• Top rated abstract ESCMID Global 2024

Publication List (if any)

new-cv4.pdf

Abstract of Research / Brief Description of Your Current Research Interest (max. 200 words)

Tick-borne encephalitis virus (TBEV) is a neurotropic virus transmitted by ticks, causing inflammation of the brain (encephalitis) in humans. With no specific antiviral treatment currently available, only symptomatic care is provided to affected individuals. My research aims to better understand the neuronal pathomechanism of TBEV infection, focusing on how the virus affects the central nervous system.

To achieve this, I utilize a multi-model approach. In vitro, I work with cell cultures to investigate cellular responses to TBEV. Ex vivo, I use organotypic brain slice cultures to study the virus’s impact on brain tissue in a more complex, 3D context. In vivo, I use Wistar rats to observe the effects of TBEV in a living organism, simulating human infection more closely.

An important goal of my research is to test several antiviral candidates using these models. Since there is currently no specific antiviral treatment for TBEV, identifying potential therapeutics could significantly improve patient outcomes and open new avenues for clinical management of the disease.

Would you like to present your Research in Poster Presentation Session and/or Flash Presentation?

Both Sessions

PART 5: OTHERS

Did you participate in the inaugural Hong Kong Laureate Forum?

N/A

How Did You Know About the Forum?

Our email