I am currently working as a postdoctoral fellowship in Prof. LYU Haitao's group at Hong Kong Baptist University, focusing on projects related to functional metabolomics and its application in
innovating therapeutic discovery of pancreatic. My purpose for joining this forum is to gain more opportunities to communicate and learn from outstanding scientists, and to meet more young scholars in this field. Such interactions can promote academic collaboration.

Hong Kong Baptist University

My research focuses on developing novel functional metabolomics Strategies and applying them to the precise diagnosis and therapeutic discovery in pancreatic cancer(PC). The lack of efficient drug targets is a major factor contributing to the insufficient number of candidate drugs available for the clinical treatment of pancreatic cancer , resulting in high mortality rates among patients. To improve survival rates and quality of life for patients, there is a strong demand to identify novel therapeutic targets for PC based on a deeper and more comprehensive understanding of its pathogenesis. Recently, with advancements in metabolomics, there has been increased focus on understanding dysregulated metabolism in cancer and how such metabolic targets can be modulated for therapeutic benefit. Therefore we are efforted to identify the determinant functional metabolites which can regulating the progression of PC, and annotate the anabolic pathway and downstream functional pathways to precisely modify the expression level of determinant functional metabolites. We have identified two potential targets for pancreatic cancer treatment in our preliminary research，citrate metabolism and AMP-cAMP axis (Pharmacological Research 2023; 187(106554) & J Proteome Res 2020; 19(9):3825-3836). Our ultimate goal is to lay the foundation for the development of new drugs and to advance clinical therapeutic strategies